RNA therapeutics for neurodegenerative diseases
Ayaan
Student · 14 years old
Arianna Dorschel
Mentor · PhD researcher, MIT/Harvard
About the project
This literature review explores RNA therapeutics such as siRNA, miRNA and antisense oligonucleotides in order to treat neurodegenerative diseases.
It focuses on Parkinson's, Alzheimer's and Spinal Muscular Atrophy, detailing their mechanisms and covering a range of possible therapeutics. It also highlights the premise and the challenges of these therapeutics.
“My mentor was extremely helpful and considerate. The entire experience was well crafted and provided ample information and guidance.”
How the project came together
- Introduction to researchGet introduced to RNA therapeutics and neurodegenerative diseases.
- Literature reviewPerform a deep dive into relevant scientific literature.
- Select focus areasChoose specific diseases: Parkinson's, Alzheimer's and Spinal Muscular Atrophy.
- Study mechanismsUnderstand the mechanisms of RNA therapeutics.
- Identify challengesAnalyse the challenges associated with RNA therapeutics.
- Draft and feedbackWrite drafts and receive feedback from the mentor.
- Revise and finaliseRevise based on feedback and finalise the research paper.
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